The NMEDW currently stores observations on more than 6.6 million distinct patients. Each day, it loads more than 2.8 billion new data elements from 142 separate sources, including electronic health records, pathology data from the hospital and research laboratories, biomarker data from research databases and research transactional data from our eIRB and other institutional systems. The NMEDW has a mature data steward model, supported by an electronic workflow that enables rapid review of data requests. It’s important to note that the older data are not always of the highest utility, and we strongly recommend that investigators who plan to use the NMEDW in their research contact the NMEDW prior to grant submission.